Photodynamic therapy in pediatric dentistry explores a cutting-edge treatment modality that has garnered significant attention in recent years. Photodynamic therapy (PDT) represents a novel approach to dental treatment, utilizing the power of light and photosensitizing agents to selectively eliminate harmful bacteria and diseased tissues within the oral cavity. This dissertation provides a comprehensive overview of PDT, its principles, clinical applications, and the immense potential it holds for pediatric dental practices. It delves into the types of photosensitizers employed, the principles of light activation, and the intricate interactions between the photosensitizer, light, and targeted tissues. The chapters that follow explore the wide range of applications of PDT in pediatric dentistry. From the treatment of dental caries and periodontal diseases to the management of oral lesions and malocclusion, the versatility of PDT becomes evident. Evidence-based guidelines, case studies, and expert opinions provide valuable insights, assisting practitioners in integrating this modality into their clinical practice.