This research was conducted under a descriptive and exploratory methodological approach, taking as reference, students enrolled in the 2020-2 semester of the Bachelor's Degree in Physical Culture and Sports of the University of Sonora, Centro Unit and the Bachelor's Degree in Education of the Santa Ana Unit, and who are in confinement due to COVID-19. The objective of this research project is to analyze the possible relationship between the levels of stress perceived by university students who are in confinement due to COVID-19 and to determine how physical activity influences the improvement of physical and psychological health to avoid stress and anxiety during the pandemic. As a conclusion, the practice of physical activity can help improve the psychological health of the student, so that it can be reflected in their academic performance.