This textbook has been prepared for publication by the Head of the Department of Normal Physiology of the Tajik State Medical University named after Abuali ibni Sino, Doctor of Medical Sciences, Professor F.A. Shukurov and Doctor of Medical Sciences, Associate Professor F.T. Halimova. Explanations for each scheme are presented in an accessible language, which ensures the assimilation of material on the relevant issues of physiology. 50 years of pedagogical experience of Shukurov F.A. and 20 years of experience of Halimova F.T. allowed to present the materials of all sections systematically and in an accessible language, which contributes to better assimilation. The use of this textbook allows to study more deeply the mechanisms underlying the functions of all systems. The use of schemes of this manual and explanations to them will allow students to understand the issues of all levels set out in the "Notebook for laboratory classes and independent work on normal physiology".