Lymphedema is a chronic disease marked by the increased collection of lymphatic fluid in the body, causing swelling, which can lead to skin and tissue changes. There are many psychological, physical, and social sequelae related to a diagnosis of lymphedema. In developed countries, most secondary lymphedema cases are due to malignancy or related to the treatment of malignancy. Lymphedema is classified as either (genetic) primary lymphedema or (acquired) secondary lymphedema.