Contents: Treatment failure due to antacids. Grapefruit juice may cause
toxic plasma concentrations of many common drugs. Warfarin. Amiodarone. All
NSAIDs (including COX-2 inhibitors). A therapeutic minefield -
spironolactone, ACEIs, NSAIDs (old and new) and all diuretics - drugs which
disrupt the fine equilibrium of renal function. Sudden cardiac collapse
caused by often-prescribed drugs causing QTc interval prolongation. Some
important interactions between drugs at shared sites of action and/or
therapeutic effect. Serious drug:drug interactions during liver metabolism.
Alcohol use (and abuse) causes two serious, little-recognized prescribing
pitfalls. Drug monitoring to avoid pitfalls - which drugs? Which tests? How
frequently? Drug-induced lung disease, often missed in primary care. Facts
the prescriber needs to know about patient non-compliance, and how to
improve compliance. Avoiding pitfalls in prescribing for elderly patients.
Clinical quizzes. Solutions.
