Fatma Megdiche, Raida Ben Salah

Place of thrombophilia assessment in retinal vein occlusion

Place of thrombophilia in the occurrence of retinal vein occlusion in southern Tunisia: about 57 cases.

• Broschiertes Buch

Produktbeschreibung

Retinal vein occlusion is the second most common retinal vasculopathy (RVO) after diabetic retinopathy. Its semiology is multifactorial. The aim of this study was to evaluate the frequency of thrombophilia and to analyze its imputability in the occurrence of RVO. Protein S and Protein C were measured by the chronometric method, antithrombin by the chromogenic method, and the statistical analysis was based on Fisher's exact test. Thrombophilia was observed in 13 patients. An isolated abnormality was noted in 11 cases: 6 polymorphisms of Factor V Leiden (FVL), five of which were heterozygous and one homozygous, three C677T polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene in the heterozygous state, and two deficiencies in PS. Our analysis statistically confirmed the involvement of hypertension, dyslipidemias, and LVF in the occurrence of RVO. Only the frequency of LVF was higher in the subgroup of patients without conventional risk factors (p=0.04). This could be due to the limited number of patients and the heterogeneity of RVO.

Produktdetails

• Verlag: Our Knowledge Publishing
• Seitenzahl: 76
• Erscheinungstermin: 22. April 2022
• Englisch
• Abmessung: 220mm x 150mm x 5mm
• Gewicht: 131g
• ISBN-13: 9786204564968
• ISBN-10: 620456496X
• Artikelnr.: 63819988

Autorenporträt

Fatma Megdiche, Doutora em Farmácia, bióloga especializada em hematologia, professora associada no Hospital Universitário Habib Bourguiba em Sfax - Faculdade de Farmácia em Monastir-Tunisia.