Plant-Based Drug Discovery

Unveiling Molecular Targets for Metabolic Conditions
Herausgeber: Srivastava, Akhileshwar Kumar; Singh, Ajay; Bisht, Mamta

• Broschiertes Buch

Produktbeschreibung

Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an overview of the molecular mechanisms of phytochemicals and how they can be utilized in the treatment of metabolic diseases. The book opens with an introduction to metabolic diseases and the significance of phytochemicals in tackling these disorders, before considering their molecular mechanisms and how they can impact health and disease. Chapters will cover topics including oxidative stress, epigenetic mechanisms, mitophagy, and targeting molecular chaperones. Molecular targets of plant nutraceuticals and phytochemical for specific treatment of obesity, cardiovascular disease and type 2 diabetes will also be covered. The book also considers technological advances such as AI and nanotechnology and their impact in this area, as well as opportunities and challenges for improving the use of plant molecules in the treatment of metabolic disorders. This is a useful book for researchers working across the fields of molecular biology, biochemistry, pharmacology, phytochemistry, drug discovery, biotechnology and related areas.

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Produktdetails

• Verlag: Elsevier Science
• Seitenzahl: 400
• Erscheinungstermin: 1. September 2025
• Englisch
• ISBN-13: 9780443316982
• ISBN-10: 0443316988
• Artikelnr.: 73226742

Inhaltsangabe

Section 1: Introduction
1. Overview of human metabolic diseases associated with lifestyle
Section 2: Phytochemicals and molecular targets
2. Significance of phytochemicals in metabolic disorders
3. Molecular connection of oxidative stress and metabolic syndrome:
Therapeutic role of phytocomponents
4. Epigenetic mechanisms of phytochemicals in cure of metabolic diseases
5. Plant¿derived bioactive peptides for treatment of metabolic disorders
6. Efficiency of phytochemicals to cure metabolic diseases by targeting
mitophagy
7. Phytochemicals as promising therapeutic approaches for
inflammasome-related metabolic diseases
8. Regulatory impact of phytochemicals on metabolic diseases by targeting
Nrf2-ARE signaling mechanism
9. Targeting molecular chaperones with phytochemicals for drug discovery in
metabolic ailments
10. Molecular targets of plant nutraceuticals against obesity
11. Molecular insight to cure cardiovascular diseases through plants
compounds
12. Mechanistic insights of important medicinal plant compounds in managing
type 2 diabetes mellitus
Section 3: Nanotechnology methods
13. Attenuation of hyperlipidemia by medicinal plants with
nanotechnological methods
Section 4: Clinical study
14. Clinical evidences of phytochemicals in cure of metabolic diseases
Section 5: Technologies and challenges for plant-based drug discovery
15. Artificial intelligence in plant-based drug discovery against metabolic
disorders
16. Integration of high-throughput omics technologies in discovery of
phytodrugs to treat metabolic diseases
17. Multi-targets drug design for screening of phytochemicals to cure of
metabolic disorders
18. New opportunities and challenges for improving the druggability of
plant product against metabolic disorders