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Nephrotoxicity should not be confused with the fact that some medications have a predominantly renal excretion and need their dose adjusted for the decreased renal function. Drug-induced nephrotoxicity can lead to acute kidney injury(AKI) or chronic kidney disease in patients and is a major problem for clinicians. Development of less nephrotoxic drugs is challenging due to the fact that the prediction of nephrotoxicity during drug development remains difficult. Typically, compound nephrotoxicity is only detected during late stages of drug development, which is associated with high costs for the pharmaceutical industry.…mehr

Produktbeschreibung
Nephrotoxicity should not be confused with the fact that some medications have a predominantly renal excretion and need their dose adjusted for the decreased renal function. Drug-induced nephrotoxicity can lead to acute kidney injury(AKI) or chronic kidney disease in patients and is a major problem for clinicians. Development of less nephrotoxic drugs is challenging due to the fact that the prediction of nephrotoxicity during drug development remains difficult. Typically, compound nephrotoxicity is only detected during late stages of drug development, which is associated with high costs for the pharmaceutical industry.
Autorenporträt
Dr. Nadia Mohamed Ahmed,Ph.D., Medical Biochemistry, Faculty of Medicine, Cairo University,Assistant professor of Medical Biochemistry, National Research center,Egypt, Experienced in experimental design, clinical Researches, DNA, PCR,have a lot of international publications,a member in international societies, Reviewer and editor in many journals.