Low female participation in higher educational institutions in Ghana has generally been seen as a major problem that needs to be addressed. This study investigated the factors that contribute to low participation of women in tertiary schools in Ghana. It also examined the challenges faced by Ghanaian women in their pursuit for higher education. Government initiatives towards girls 'higher education` have also been explored. The study used mainly qualitative and to some extent quantitative methods, thus interview and field notes. Students, parents, faculty members and some officials at the Ministry of education in Ghana were interviewed in order to understand their views towards the kind of policies needed to increase the participation of women in higher education in Ghana.