The reason of inclination of the researchers towards the herbal system for the treatment of many ailments is the high cost involved with manufacturing the modern medicines. This research work has also been designed on the same philosophy by selecting the most widely used edible herbs for development of herbal formulations. All the three herbs; Lagenaria siceraria, Trichosanthus dioica and Abelmoschus esculentus were phyto-pharmacologically screened and on the basis of the outcome polyherbal conventional topical formulations were developed for the treatment of inflammation. The researcher had also developed the transdermal polyherbal drug delivery system, a novel approach to deliver phyto-constituents to the system thorough dermis avoiding many drawbacks of the oral delivery systems and registering better patient compliance. I believe this comprehensive textbook will be of use and great value to the students, academicians, researchers and herbal drug industry.