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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. A position weight matrix (PWM), also called position-specific weight matrix (PSWM) or position-specific scoring matrix (PSSM), is a commonly used representation of motifs (patterns) in biological sequences. A PWM is a matrix of score values that gives a weighted match to any given substring of fixed length. It has one row for each symbol of the alphabet, and one column for each position in the pattern. The score assigned by a PWM to a substring s=(s_j)_{j=1}^N is…mehr

Produktbeschreibung
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. A position weight matrix (PWM), also called position-specific weight matrix (PSWM) or position-specific scoring matrix (PSSM), is a commonly used representation of motifs (patterns) in biological sequences. A PWM is a matrix of score values that gives a weighted match to any given substring of fixed length. It has one row for each symbol of the alphabet, and one column for each position in the pattern. The score assigned by a PWM to a substring s=(s_j)_{j=1}^N is defined as textstyle sum_{j=1}^{N}{m_{s_j,j}}, where j represents position in the substring, sj is the symbol at position j in the substring, and m ,j is the score in row , column j of the matrix. In other words, a PWM score is the sum of position-specific scores for each symbol in the substring.