Positive Airway Pressure (PAP) Therapy is a hugely important therapy option for sleep medicine specialists. This issue examines PAP therapy from every angle, in adults and children, to deliver a collection of up-to-the-minute reviews for the clinician. Topics include PAP Adherence, PAP treatment of OSA in adults and children (two separate articles), CPAP/BPAP titration, Adaptive Servo-Ventilation Titration, APAP and alternative titration methods, PAP treatment of Central Sleep Apnea, PAP and CHF, PAP treatment of hypoventilation in children, effects of PAP treatment on Non-CV medical disorders and on cardiovascular function, Adjunctive measures in PAP (oxygen, humidification, hypnotics) and NPPV titration and treatment.