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High Quality Content by WIKIPEDIA articles! The positive predictive value, or precision rate, or post-test probability of disease, is the proportion of patients with positive test results who are correctly diagnosed. It is the most important measure of a diagnostic method as it reflects the probability that a positive test reflects the underlying condition being tested for. Its value does however depend on the prevalence of the disease, which may vary.Hence with large numbers of false positives and few false negatives, a positive FOB screen test is in itself poor at confirming cancer (PPV = 10%) and further investigations must be undertaken, it will, however, pick up 66.7% of all cancers (the sensitivity). However as a screening test, a negative result is very good at reassuring that a patient does not have cancer (NPV = 99.5%) and at this initial screen correctly identifies 91% of those who do not have cancer (the specificity).