Serum cardiac troponin (cTnI) and creatinine kinase-MB (CK-MB) levels are now widely used in the diagnosis of myocardial infarct (MI) and injury in living patients, but their utility in postmortem diagnosis has not been established. Determination the specificity of the cTnI and CK-MB assay by using peripheral and pericardial blood samples compared with microscopic cardiac pathology for diagnosis of myocardial infarction in sudden deaths, and to find out whether it is practical and significant enough to estimate post-mortem interval by analyzing quantitatively the pericardial enzyme activity changes.
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