This book Practical Medicinal Chemistry is intended for use in undergraduate pharmacy course on medicinal chemistry where there is a need to appreciate the rationales behind the synthesis of drugs. It provides a suitable background for graduates in chemistry who are just entering the pharmaceutical industry. In lecture, they will learn the principles and theories that, to date, best explain the observations that have accumulated. The problem is that, it is easy to forget that these theories apply to the real world. The laboratory experience is by design your opportunity to see these principles and theories in practice. This practical manual has been written not only to enhance students' understanding of chemistry, but also to capture data and take observations. The emphasis in this book is on principles, which are appropriately illustrated by groups of drugs in current use. This approach should provide the newly qualified graduates with an understanding of new developments as they take place in future years.