Chromatin immunoprecipitation sequencing (ChIP-seq) is amongst the most widely used methods in molecular biology. This practical book guides experimental biologists and bioinformaticians through the points one needs to consider when designing such a study and the analysis steps from quality control to visualisation.
Chromatin immunoprecipitation sequencing (ChIP-seq) is amongst the most widely used methods in molecular biology. This practical book guides experimental biologists and bioinformaticians through the points one needs to consider when designing such a study and the analysis steps from quality control to visualisation.
Borbala Mifsud is an assistant professor in Epigenomics at the Hamad Bin Khalifa University, Doha, Qatar. She is a computational biologist with a background in molecular biology and works on 3D chromatin conformation and the integration of epigenomic data. Kathi Zarnack is a principal investigator in Computational RNA Biology at the Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt, Germany. She is a computational biologist with a background in molecular biology and broad experience in analysing high-throughput sequencing data. Anaïs F Bardet is a tenured researcher at the National Center for Scientific Research (CNRS) at the University of Strasbourg, France. She is a computational biologist and develops projects exploring the regulation of transcription factor binding.
Inhaltsangabe
Chapter 1 Introduction to ChIP-seq Chapter 2 Getting Started Chapter 3 General Quality Control Chapter 4 Genomic Alignment Chapter 5 ChIP-seq-specific Quality Control Chapter 6 Peak Calling Chapter 7 Data visualisation Chapter 8 Comparative Analysis Chapter 9 Downstream Analyses
