Practical Transfusion Medicine Practical Transfusion Medicine, Sixth Edition The pace of change in transfusion medicine is relentless, with new scientific and technological developments and continuing efforts to improve transfusion practice. This sixth edition of Practical Transfusion Medicine has been updated significantly to reflect the rapid changes in transfusion medicine since the fifth edition was published in 2017. The primary purpose of this edition remains the same as the first: to provide a comprehensive guide to transfusion medicine. This book contains more depth of…mehr
The pace of change in transfusion medicine is relentless, with new scientific and technological developments and continuing efforts to improve transfusion practice. This sixth edition of Practical Transfusion Medicine has been updated significantly to reflect the rapid changes in transfusion medicine since the fifth edition was published in 2017.
The primary purpose of this edition remains the same as the first: to provide a comprehensive guide to transfusion medicine. This book contains more depth of information than standard handbooks on transfusion medicine, whilst being more concise and approachable than a standard reference text.
This book covers the principles of transfusion medicine, the complications of transfusion, practice in blood centres and hospitals and clinical transfusion practice. This sixth edition includes a new section on patient blood management, cellular and tissue therapy, organ transplantation and the development of the evidence base for transfusion. It also features a new chapter on transfusion-associated circulatory overload to underline its importance as a complication of transfusion, and a reconfiguration of the section on clinical transfusion practice to allow consideration of the transfusion management of medical, surgical and haematology patients with and without bleeding.
This sixth edition of Practical Transfusion Medicine provides accessible and comprehensive coverage of the field of transfusion medicine. It is a standalone text that will be useful to clinical and scientific staff: not only for trainees who require an overview of the field, but also for established practitioners who are involved in some aspect of transfusion medicine and require a comprehensive, accessible reference book.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
About the Editors Michael F. Murphy, MD, FRCP, FRCPath, FFPath, is Professor of Blood Transfusion Medicine at the University of Oxford, and Consultant Haematologist for NHS Blood and Transplant and the Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. David J. Roberts, MB, ChB, DPhil, FRCPath, is Professor of Haematology at the University of Oxford, Medical Director for Pathology for NHS Blood and Transplant and also works as a Consultant Haematologist in the Department of Haematology, John Radcliffe Hospital, Oxford, UK. Mark H. Yazer, MD is Professor of Pathology at the University of Pittsburgh, an Adjunct Professor of Clinical Immunology at the University of Southern Denmark, Odense, Denmark, and a Visiting Professor of Pathology at Tel Aviv University. His research interest is in blood use in massive bleeding. Nancy M. Dunbar, MD is Associate Professor of Pathology and Laboratory Medicine at the Geisel School of Medicine at Dartmouth and serves as the Medical Director of the Blood Bank at Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Inhaltsangabe
List of Contributors ix
Preface to the Sixth Edition xvi
1 Introduction: Two Centuries of Progress in Transfusion Medicine 1 Walter H. (Sunny) Dzik and Michael F. Murphy
Part I Basic Principles of Immunohaematology 11
2 Essential Immunology for Transfusion Medicine 11 Gregory A. Denomme
3 Human Blood Group Systems 21 Geoff Daniels and Sean Stowell
4 Human Leukocyte Antigens 33 H. Cliff Sullivan and Caroline R. Alquist
5 Platelet and Neutrophil Antigens 47 Brian R. Curtis
6 Pretransfusion Testing and the Selection of Red Cell Products for Transfusion 64 Mark H. Yazer, Meghan Delaney and Gregory A. Denomme Copyrighted Material
Part II Complications of Transfusions 77
7 Investigation of Acute Transfusion Reactions 77 Heather Leary, Kathryn E. Webert and Nancy M. Heddle
8 Haemolytic Transfusion Reactions 91 Edwin J. Massey, Robertson D. Davenport and Richard M. Kaufman
9 Febrile and Allergic Transfusion Reactions 108 Sarah K. Harm and Mark K. Fung
10 Transfusion- Associated Circulatory Overload 120 Robert B. Klanderman and Alexander P.J. Vlaar
11 Transfusion- Related Acute Lung Injury (TRALI) 130 Alexander P.J. Vlaar and Rick Kapur
12 Purported Adverse Effects of 'Old Blood' 145 Lirong Qu and Darrell J. Triulzi
13 Transfusion- Induced Immunomodulation 154 Neil Blumberg, Majed A. Refaai and Joanna M. Heal
14 Transfusion- Associated Graft- versus- Host Disease and Microchimerism 166 Alexandra Budhai, Richard O. Francis and Beth H. Shaz
15 Posttransfusion Purpura 181 Michael F. Murphy
16 Heparin- Induced Thrombocytopenia 187 Theodore E. Warkentin and Andreas Greinacher
17 Transfusion- Transmitted Infections 206 Steven J. Drews and Roger Y. Dodd
18 Bacterial Contamination 221 Sandra Ramírez- Arcos and Mindy Goldman
19 Emerging Infections and Transfusion Safety 229 Roger Y. Dodd
Part III Practice in Blood Centres and Hospitals 238
20 Regulatory Aspects of Blood Transfusion 238 Louis M. Katz, Peter Flanagan and William G. Murphy
21 The Role of Hemovigilance in Transfusion Safety 247 Katharine A. Downes and Barbee I. Whitaker
22 Donors and Blood Collection 257 Marc Germain and Pierre Tiberghien
23 Blood Donation Testing and the Safety of the Blood Supply 269 Mindy Goldman and Steven J. Drews
24 Production and Storage of Blood Components 278 Marissa Li, Rebecca Cardigan, Stephen Thomas and Ralph Vassallo
25 Blood Transfusion in Hospitals 290 Zoe K. McQuilten, Erica M. Wood, Mark H. Yazer and Michael F. Murphy
26 Disaster Preparedness 313 Heidi Doughty, Fateha Chowdhury and Richard Rackham
27 Blood Transfusion in a Global Context 324 David J. Roberts, Imelda Bates, Stephen P. Field, Aggrey Dhabangi, Jean Pierre Allain and Meghan Delaney
Part IV Clinical Transfusion Practice 337
28 Inherited and Acquired Disorders of Haemostasis 337 Irina Chibisov, Jansen Seheult and Franklin Bontempo
29 Point- of- Care Haemostasis Testing 353 Katrina M. Morgan, Matthew D. Neal, Louis Alarcon and Christine M. Leeper
30 Transfusion in Bleeding Patients 365 Aaron S. Hess, Lynn G. Stansbury and John R. Hess
31 Transfusion in Non- Bleeding Medical and Surgical Patients 374 Killian Donovan, Akshay Shah, Stuart McKechnie and Simon J. Stanworth
32 Transfusion in Malignant Haematological Disease 385 Lise J. Estcourt and Michael F. Murphy
33 Transfusion in Benign Haematological Disease 399 Eric Salazar and Christopher A. Tormey
1 Introduction: Two Centuries of Progress in Transfusion Medicine 1 Walter H. (Sunny) Dzik and Michael F. Murphy
Part I Basic Principles of Immunohaematology 11
2 Essential Immunology for Transfusion Medicine 11 Gregory A. Denomme
3 Human Blood Group Systems 21 Geoff Daniels and Sean Stowell
4 Human Leukocyte Antigens 33 H. Cliff Sullivan and Caroline R. Alquist
5 Platelet and Neutrophil Antigens 47 Brian R. Curtis
6 Pretransfusion Testing and the Selection of Red Cell Products for Transfusion 64 Mark H. Yazer, Meghan Delaney and Gregory A. Denomme Copyrighted Material
Part II Complications of Transfusions 77
7 Investigation of Acute Transfusion Reactions 77 Heather Leary, Kathryn E. Webert and Nancy M. Heddle
8 Haemolytic Transfusion Reactions 91 Edwin J. Massey, Robertson D. Davenport and Richard M. Kaufman
9 Febrile and Allergic Transfusion Reactions 108 Sarah K. Harm and Mark K. Fung
10 Transfusion- Associated Circulatory Overload 120 Robert B. Klanderman and Alexander P.J. Vlaar
11 Transfusion- Related Acute Lung Injury (TRALI) 130 Alexander P.J. Vlaar and Rick Kapur
12 Purported Adverse Effects of 'Old Blood' 145 Lirong Qu and Darrell J. Triulzi
13 Transfusion- Induced Immunomodulation 154 Neil Blumberg, Majed A. Refaai and Joanna M. Heal
14 Transfusion- Associated Graft- versus- Host Disease and Microchimerism 166 Alexandra Budhai, Richard O. Francis and Beth H. Shaz
15 Posttransfusion Purpura 181 Michael F. Murphy
16 Heparin- Induced Thrombocytopenia 187 Theodore E. Warkentin and Andreas Greinacher
17 Transfusion- Transmitted Infections 206 Steven J. Drews and Roger Y. Dodd
18 Bacterial Contamination 221 Sandra Ramírez- Arcos and Mindy Goldman
19 Emerging Infections and Transfusion Safety 229 Roger Y. Dodd
Part III Practice in Blood Centres and Hospitals 238
20 Regulatory Aspects of Blood Transfusion 238 Louis M. Katz, Peter Flanagan and William G. Murphy
21 The Role of Hemovigilance in Transfusion Safety 247 Katharine A. Downes and Barbee I. Whitaker
22 Donors and Blood Collection 257 Marc Germain and Pierre Tiberghien
23 Blood Donation Testing and the Safety of the Blood Supply 269 Mindy Goldman and Steven J. Drews
24 Production and Storage of Blood Components 278 Marissa Li, Rebecca Cardigan, Stephen Thomas and Ralph Vassallo
25 Blood Transfusion in Hospitals 290 Zoe K. McQuilten, Erica M. Wood, Mark H. Yazer and Michael F. Murphy
26 Disaster Preparedness 313 Heidi Doughty, Fateha Chowdhury and Richard Rackham
27 Blood Transfusion in a Global Context 324 David J. Roberts, Imelda Bates, Stephen P. Field, Aggrey Dhabangi, Jean Pierre Allain and Meghan Delaney
Part IV Clinical Transfusion Practice 337
28 Inherited and Acquired Disorders of Haemostasis 337 Irina Chibisov, Jansen Seheult and Franklin Bontempo
29 Point- of- Care Haemostasis Testing 353 Katrina M. Morgan, Matthew D. Neal, Louis Alarcon and Christine M. Leeper
30 Transfusion in Bleeding Patients 365 Aaron S. Hess, Lynn G. Stansbury and John R. Hess
31 Transfusion in Non- Bleeding Medical and Surgical Patients 374 Killian Donovan, Akshay Shah, Stuart McKechnie and Simon J. Stanworth
32 Transfusion in Malignant Haematological Disease 385 Lise J. Estcourt and Michael F. Murphy
33 Transfusion in Benign Haematological Disease 399 Eric Salazar and Christopher A. Tormey
34 Transfusion in Patients with Haemoglobino
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