
Precision Crystallization
Theory and Practice of Controlling Crystal Size
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This book discusses modeling the nucleation process of particles through the balanced nucleation-growth (BNG) process, a subject which has been touched upon in articles but rarely in a comprehensive book format. The BNG model allows the quantification of the nucleation rate, maximum growth rate, and supersaturation during the nucleation period as a function of nucleation efficiency and maximum growth rate of the crystals. From this model, equations are derived that correlate the number of stable crystals formed with molar addition rate of reactants, solubility of the crystals, and temperature....
This book discusses modeling the nucleation process of particles through the balanced nucleation-growth (BNG) process, a subject which has been touched upon in articles but rarely in a comprehensive book format. The BNG model allows the quantification of the nucleation rate, maximum growth rate, and supersaturation during the nucleation period as a function of nucleation efficiency and maximum growth rate of the crystals. From this model, equations are derived that correlate the number of stable crystals formed with molar addition rate of reactants, solubility of the crystals, and temperature. The fundamental aspects of physical chemistry pertaining to this process are also reviewed.