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This book demonstrates the deleterious effects of hydrosalpinx on fertilization, implantation, tubal physiology and endometrium, different diagnostic tools of hydrosalpinx, surgical management versus assisted reproduction, conservative and radical management, several technical details of different laparoscopic lines of management and stratify management plan based on both evidence-based medicine (EBM) and precision medicine (PM). After detailed discussion, this book concluded that individualized surgical treatment (precision medicine) of hydrosalpinx is highly recommended based on strict preoperative and intraoperative criteria.