Preclinical Drug Development
Herausgeber: Taft, David R.; Rogge, Mark
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Preclinical Drug Development
Herausgeber: Taft, David R.; Rogge, Mark
- Gebundenes Buch
Preclinical Drug Development
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Produktdetails
- Produktdetails
- Drugs and the Pharmaceutical Sciences
- Verlag: Taylor & Francis Inc
- 2 ed
- Seitenzahl: 380
- Erscheinungstermin: 25. September 2009
- Englisch
- Abmessung: 259mm x 181mm x 33mm
- Gewicht: 966g
- ISBN-13: 9781420084726
- ISBN-10: 1420084720
- Artikelnr.: 23611198
- Drugs and the Pharmaceutical Sciences
- Verlag: Taylor & Francis Inc
- 2 ed
- Seitenzahl: 380
- Erscheinungstermin: 25. September 2009
- Englisch
- Abmessung: 259mm x 181mm x 33mm
- Gewicht: 966g
- ISBN-13: 9781420084726
- ISBN-10: 1420084720
- Artikelnr.: 23611198
Mark Rogge, David R. Taft
The Scope of Preclinical Drug Development: An Introduction and
Framework.Lead Molecule Selection: Pharmaceutical Profiling and Toxicity
Assessments.Interspecies Differences in Physiology and Pharmacology:
Extrapolating Preclinical Data to Human Populations.Pharmacokinetics/ADME
of Small Molecules.Pharmacokinetics/ADME of Large Molecules.Preclinical
Pharmacokinetic-Pharmacodynamic Modeling and Simulation in Drug
Development.Formulation and Production Strategies for Enhancing
Bioavailability of Poorly Absorbed Drugs. Transporters Involved in Drug
Disposition, Toxicity, and Efficacy. Toxicity Evaluations, ICH Guidelines,
and Current Practice.Application of Pathology in Safety
Assessment.Utilizing the Preclinical Database to Support Clinical Drug
Development. Index.
Framework.Lead Molecule Selection: Pharmaceutical Profiling and Toxicity
Assessments.Interspecies Differences in Physiology and Pharmacology:
Extrapolating Preclinical Data to Human Populations.Pharmacokinetics/ADME
of Small Molecules.Pharmacokinetics/ADME of Large Molecules.Preclinical
Pharmacokinetic-Pharmacodynamic Modeling and Simulation in Drug
Development.Formulation and Production Strategies for Enhancing
Bioavailability of Poorly Absorbed Drugs. Transporters Involved in Drug
Disposition, Toxicity, and Efficacy. Toxicity Evaluations, ICH Guidelines,
and Current Practice.Application of Pathology in Safety
Assessment.Utilizing the Preclinical Database to Support Clinical Drug
Development. Index.
The Scope of Preclinical Drug Development: An Introduction and
Framework.Lead Molecule Selection: Pharmaceutical Profiling and Toxicity
Assessments.Interspecies Differences in Physiology and Pharmacology:
Extrapolating Preclinical Data to Human Populations.Pharmacokinetics/ADME
of Small Molecules.Pharmacokinetics/ADME of Large Molecules.Preclinical
Pharmacokinetic-Pharmacodynamic Modeling and Simulation in Drug
Development.Formulation and Production Strategies for Enhancing
Bioavailability of Poorly Absorbed Drugs. Transporters Involved in Drug
Disposition, Toxicity, and Efficacy. Toxicity Evaluations, ICH Guidelines,
and Current Practice.Application of Pathology in Safety
Assessment.Utilizing the Preclinical Database to Support Clinical Drug
Development. Index.
Framework.Lead Molecule Selection: Pharmaceutical Profiling and Toxicity
Assessments.Interspecies Differences in Physiology and Pharmacology:
Extrapolating Preclinical Data to Human Populations.Pharmacokinetics/ADME
of Small Molecules.Pharmacokinetics/ADME of Large Molecules.Preclinical
Pharmacokinetic-Pharmacodynamic Modeling and Simulation in Drug
Development.Formulation and Production Strategies for Enhancing
Bioavailability of Poorly Absorbed Drugs. Transporters Involved in Drug
Disposition, Toxicity, and Efficacy. Toxicity Evaluations, ICH Guidelines,
and Current Practice.Application of Pathology in Safety
Assessment.Utilizing the Preclinical Database to Support Clinical Drug
Development. Index.