Henner Schmidt-Traub (Hrsg.)

Preparative Chromatography of Fine Chemicals and Pharmaceutical Agents

Herausgegeben:Schmidt-Traub, Henner

• Gebundenes Buch

Produktbeschreibung

Die präparative Chromatographie ist ein Verfahren zur Reinigung auch kleiner Mengen von Produkten in kürzester Zeit. In diesem interdisziplinär angelegten Band erfahren Chemiker und Ingenieure, was sie im Alltag über naturwissenschaftliche und technologische Grundlagen dieser Methode wissen müssen und wie sie chromatographische Prozesse optimieren können. Dabei wird die Arbeit im Labormaßstab ebenso berücksichtigt wie die Konzeption industrieller Anlagen.-Derzeit gibt es am Markt kein anderes Buch mit ähnlichem Themenspektrum.

Produktdetails

• Verlag: Wiley-VCH
• Seitenzahl: 300
• Englisch
• Abmessung: 246mm x 186mm x 29mm
• Gewicht: 1042g
• ISBN-13: 9783527306435
• ISBN-10: 3527306439
• Artikelnr.: 12060050

Autorenporträt

Henner Schmidt-Traub, Prof. Dr.-Ing. habil.
Industrial activities in plant engineering for 15 years
Since 1989 Professor for Plant and Process Design
Department of Biochemical and Chemical Engineering, University of Dortmund
Research: Preparative chromatography, Down stream processing, Integrated processes, Plant design, Innovative energy transfer

Inhaltsangabe

INTRODUCTION
Liquid Chromatography - It's History
Focus of the Book
How to read this Book?
FUNDAMENTALS AND GENERAL TERMINOLOGY
Principles of Adsorption Chromatography
Basic Effects and Chromatographic Definitions
Fluid Dynamics
Mass Transfer Phenomena
Equilibrium Thermodynamics
Thermodynamic Effects on Mass Separation
Practical Aspects of Parameter Determination
COLUMNS, PACKINGS AND STATIONARY PHASES
Column Design
Column Packings
Column Packing Technology
Column Testing
Column Maintenance and Regeneration
Guidelines for Choosing Chromatographic Columns and Stationary Phases
SELECTION OF CHROMATOGRAPHIC SYSTEMS
Definition of the Task
Properties of Chromatographic Systems
Criteria for the Choice of Chromatographic Systems
PROCESS CONCEPTS
Design and Operation of Equipment
Discontinuous Processes
Continuous Processes
Guidelines
MODELLING AND DETERMINATION OF MODEL PARAMETERS
Introduction
Models for Single Chromatographic Columns
Modelling HPLC Plants
Numerical Methods
Parameter Determination
Validation of Column Models
Modelling of SMB-Processes
MODEL BASED DESIGN AND OPTIMISATION
Basic Principles
Batch Chromatography
SMB Chromatography
Comparison of Batch and SMB Chromatography
CHROMATOGRAPHIC REACTORS
Introduction
Types of Chromatographic Reactors
Modelling of Chromatographic Reactors
Operation and Design of Chromatographic Reactors
Design Examples
ADVANCED CONTROL OF SIMULATED MOVING BED PROCESSES
Introduction
Model Predictive Control
State of the Art in Control of Simulated Moving Bed Processes
Online Optimising Control of a Reactive Simulated Moving Bed Process
Conclusions
APPENDIX

Rezensionen

" - I would not hesitate to recommend it to anyone working in this field." - Chromatographia

" - Overall the coverage is a bit uneven - nevertheless the volume does compile some useful material... In conclusion, this is a comprehensive reference text, which should find its way into the libraries of all companies who are serious about process scale preparative chromatography, whether internally or via outsource contracts." - Organic Process Research and Development

" - This special volume is essential for chemists and engineers working in chemical and pharmaceutical industries, as well as for food technologies, due to the interdisciplinary nature of these preparative chromatographic processes." - Advances in Food Sciences