Preparative Enantioselective Chromatography - Cox Geoff
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The development of chiral liquid chromatography, facilitating the straightforward separation of enantiomers, was a significant advance in chromatography, leading to widespread application in analytical chemistry. Application in preparative chromatography has been less rapid, but with the development of single enantiomer pharmaceuticals its use is increasingly common in chemical synthesis at laboratory, pilot plant and even full production scale. Written for chemists, chemical engineers and analytical chemists, Preparative Enantioselective Chromatography demonstrates the considerable utility of…mehr

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Produktbeschreibung
The development of chiral liquid chromatography, facilitating the straightforward separation of enantiomers, was a significant advance in chromatography, leading to widespread application in analytical chemistry. Application in preparative chromatography has been less rapid, but with the development of single enantiomer pharmaceuticals its use is increasingly common in chemical synthesis at laboratory, pilot plant and even full production scale. Written for chemists, chemical engineers and analytical chemists, Preparative Enantioselective Chromatography demonstrates the considerable utility of the technique in contemporary discovery, development and production scale chemistry. By briefly covering basic preparative chromatography then developing the discussion to cover chiral stationary phases for preparative use, method development and practical applications, the first part of this book serves as an ideal introduction to the technology for laboratory and pilot plant scale application. The more detailed information presented in the later chapters, on applications in discovery, process development and large scale or production environments, including case studies and equipment selection issues, ensures the book will serve as a sound reference for experienced separation scientists.
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Autorenporträt
Dr Geoffrey B Cox (Editor)VP & General Manager, Separation Solutions
Rezensionen
"With such a good coverage of the topics and a generous collectionof references, the book is a pleasure to read and refer to. Thebook has struck almost exactly the right note in attractiveness ofpurpose and method of presentation. The book has a distinctlyreadable quality.
Both the editor and the authors are to be commended for sharingtheir insights and experience in such an easily accessedvolume.
The entire volume is lavishly illustrated with tables, graphs anddrawings, the design and execution and placement of which are asperfect as the text material they illustrate."
Current Engineering Practice

'The book is a delight to read.'

'Cox's book provides chemists and chemical engineers withvaluable hints and advises. The authors are, in part, experiencedpractitioners in the industry and academics at the forefront ofthis field...at every stage, material is logically presented andeasy to access.'

'In summary, this is an excellent compiled book withwell-produced text'

Gregor Mann, Organic Process Research and Development,September 2005

"This book represents a valuable source of information on themultifaceted challenges one may encounter when performingpreparative chromatographic enantiomer seperations, and large-scalechromatography in general ... [this] account will be warmlywelcomed by clientele from both industry and academia, as it offersinsightful and enjoyable reading, even to the expert."
Analytical and Bioanalytical Chemistry…mehr