Hepatic impairment in CD represents a broad spectrum, ranging from moderate to severe hepatic dysfunction. It presents in two clinical forms: cryptogenic hepatopathy and dysimmune hepatopathy. Epidemiological studies have shown that the prevalence of CD in the cirrhotic population is higher than in the general population. It has also been shown that CD may be at the origin of chronic cryptogenic liver disease, which may improve after initiation of GFR even at the stage of cirrhosis.