According to World Health Organization, stroke is defined as a group of disorders of brain and blood vessels that develops rapidly with the clinical signs and the disturbances of the cerebral functions lasting for 24 hours or longer leading to death, which occurs with a vascular origin. The modifiable risk factors that contributed for stroke in India are demographic, socioeconomic and life style. The non-modifiable risk factors for occurrence of stroke are sex, age, ethnic, race, genetic factors and low birth weight. In India diabetes, hypertension, heart disease, smoking and long term alcohol consumption are major risk factors of stroke. The choice or decision of drug therapy given is based on the patient condition. The prescribing pattern and treatment therapy mainly involves drugs like anticoagulants, thrombolytics, angiotensin receptor blockers, antihypertensives, diuretics, statins, cerebral activators and antiplatelet drugs.