Primitive Neuroectodermal Tumor
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High Quality Content by WIKIPEDIA articles! Primitive neuroectodermal tumor (PNET) is a neural crest tumor. It is a rare tumor, usually occurring in children under 10 years old. It has a survival rate of less than 40%. It gets its name because the majority of the cells in the tumor are derived from neuroectoderm, but have not developed and differentiated in the way a normal neuron would, and so the cells appear "primitive". For example, medulloblastoma is now known to derive from neural stem cell precursors, but because of the unusual appearance, for years it was thought to be a glioma. PNET…mehr

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High Quality Content by WIKIPEDIA articles! Primitive neuroectodermal tumor (PNET) is a neural crest tumor. It is a rare tumor, usually occurring in children under 10 years old. It has a survival rate of less than 40%. It gets its name because the majority of the cells in the tumor are derived from neuroectoderm, but have not developed and differentiated in the way a normal neuron would, and so the cells appear "primitive". For example, medulloblastoma is now known to derive from neural stem cell precursors, but because of the unusual appearance, for years it was thought to be a glioma. PNET belongs to the Ewing family of tumors. Ependymoblastoma is a synonym for PNET. It is classified into two types, based on location in the body: peripheral PNET and CNS PNET. It is also possible to add a third category, involving tumors of the autonomic nervous system, such as neuroblastoma.