Ein Gewinn insbesondere für Leser, die ihre Kenntnisse in klassischer und moderner Biochemie mit Grundlagenwissen der Chemie untermauern wollen, präsentiert der Band "harte Fakten" zu chemischen Mechanismen in biomolekularen Strukturen in ansprechender Aufbereitung. Das "Voet-Autorenteam" ist das auflagenstärkste im Bereich Biochemie. Auf stolzen 1.264 Seiten präsentiert es hier, in der gründlich überarbeiteten und aktualisierten Auflage ihres Standardwerkes, die Grundlagen des Fachs. Die Schwerpunkte des Lehrbuchs bilden die Struktur von Biomolekülen, chemische Mechanismen sowie…mehr
Ein Gewinn insbesondere für Leser, die ihre Kenntnisse in klassischer und moderner Biochemie mit Grundlagenwissen der Chemie untermauern wollen, präsentiert der Band "harte Fakten" zu chemischen Mechanismen in biomolekularen Strukturen in ansprechender Aufbereitung.Das "Voet-Autorenteam" ist das auflagenstärkste im Bereich Biochemie. Auf stolzen 1.264 Seiten präsentiert es hier, in der gründlich überarbeiteten und aktualisierten Auflage ihres Standardwerkes, die Grundlagen des Fachs. Die Schwerpunkte des Lehrbuchs bilden die Struktur von Biomolekülen, chemische Mechanismen sowie evolutionäre Beziehungen. Neue Erkenntnisse der Forschung werden in Kapiteln zu Genomik oder Strukturbiologie gebündelt. In der aktuellen Auflage hinzugekommen sind Abschnitte zu zytoskeletalen und motorischen Proteinen, die in der Forschungspraxis immer mehr an Bedeutung gewinnen. Die Darstellung der Inhalte erhält eine besondere Transparenz durch Exkurse in die Geschichte der Biochemie, die ein tieferes Verständnis der Werkzeuge und Methoden des Fachs ermöglichen. Den Autoren gelingt es, eben die Begeisterung für das Fach zu vermitteln, die die Grundlage für viele Erfolge der Spitzenforschung war und ist.
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Autorenporträt
Donald Voet received a B.S. in Chemistry from the California Institute of Technology, a Ph.D. in Chemistry from Harvard University with William Lipscomb, and did postdoctoral research in the Biology Department at MIT with Alexander Rich. Upon completion of his postdoctoral research, Don took up a faculty position in the chemistry Department at the University of Pennsylvania where, for the past 38 years, he has taught a variety of biochemistry courses as well as general chemistry. His major area of research is the X-ray crystallography of molecules of biological interest. he has been a visiting scholar at Oxford University, The University of California at San Diego, and the Weizmann Institute of Science in Israel. Together with Judith G. Voet, he is Co-Editor-in-Chief of the journal biochemistry and Molecular Biology Education. He is a member of the Education Committee of the International Union of biochemistry and Molecular Biology. His hobbies include backpacking, scuba diving, skiing, travel, photography, and writing biochemistry textbooks.
Judith ('Judy") Voet received her B.S. in Chemistry from Antioch College and her Ph.D. in Biochemistry from Brandeis University with Robert H. Abeles. She has done postdoctoral research at the University of Pennsylvania, Haverford College, and the Fox Chase Cancer Center. Her main area of research involves enzyme reaction mechanisms and inhibition. She taught biochemistry at the University of Delaware before moving to Swarthmore College. She taught There for 26 years, reaching the position of James H. Hammons Professor of chemistry and Biochemistry before going on "permanent sabbatical leave." She has been a visiting scholar at Oxford University, University of California, San Diego, University of Pennsylvania, and the Weizmann Institute of Science, Israel. She is Co-Editor-in-Chief of the journal Biochemistry and Molecular Biology Education. She has been a member of the Education and Professional Development Committee of the American Society for Biochemistry and Molecular Biology as well as the Education Committee of the International Union of Biochemistry and Molecular Biology. Her hobbies include biochemistry and Molecular biology. Her hobbies include hiking, backpacking, scuba diving, and tap dancing.
Charlotte Pratt received her B.S. in Biology from the University of Notre Dame and her Ph.D. in Biochemistry from Duke University under the direction of Salvatore Pizzo. Although she originally intended to be a marine biologist, she discovered that Bi8ochemsitry offered the most compelling answers to many 3uesitns about biological structure-function relationships and the molecular basis for human health and disease. She conducted postdoctoral researching the Center for Thrombosis and Hemostasis at the University of North Carolina at Chapel Hill. She has taught at the University of Washington and currently teaches at Seattle Pacific University. In addition to working as an editor of several biochemistry textbooks, she has co-authored Essential Biochemistry and previous editions of Fundamentals of Biochemistry.
Inhaltsangabe
PART I: INTRODUCTION.
Chapter 1. Introduction to the Chemistry of Life.
Chapter 2. Water.
PART II: BIOMOLECULES.
Chapter 3. Nucleotides, Nucleic Acids, and Genetic Information.
Chapter 4. Amino Acids.
Chapter 5. Proteins: Primary Structure.
Chapter 6. Proteins: Three-Dimensional Structure.
Chapter 7. Protein Function Part I: Myoglobin and Hemoglobin.
Chapter 8. Carbohydrates.
Chapter 9. Lipids and Biological Membranes.
Chapter 10. Membrane Transport.
PART III: ENZYMES.
Chapter 11. Enzymatic Catalysis.
Chapter 12. Enzyme Kinetics, Inhibition, and Regulation.
PART IV: METABOLISM.
Chapter 13. Introduction to Metabolism.
Chapter 14. Glucose Catabolism.
Chapter 15. Glycogen Metabolism and Gluconeogenesis.
Chapter 16. Citric Acid Cycle.
Chapter 17. Electron Transport and Oxidative Phosphorylation.
Chapter 18. Photosynthesis.
Chapter 19. Lipid Metabolism.
Chapter 20. Amino Acid Metabolism.
Chapter 21. Mammalian Fuel Metabolism: Integration and Regulation.
Chapter 22. Nucleotide Metabolism.
PART V: GENE EXPRESSION AND REPLICATION.
Chapter 23. Nucleic Acid Structure.
Chapter 24. DNA Replication, Repair, and Recombination.
Chapter 25. Transcription and RNA Processing.
Chapter 26. Translation.
Chapter 27. Regulation of Gene Expression.
Chapter 28. Protein Function Part II: Cytoskeletal and Motor Proteins and Antibodies.