Nsiah, F: Probing Protein Adsorption on Model Surfaces
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- Englisch ausgewählt
49,00 €
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Beschreibung
Produktdetails
Einband
Taschenbuch
Verlag
VDMSeitenzahl
124
Maße (L/B/H)
0,7/15/22 cm
Gewicht
182 g
Sprache
Englisch
ISBN
978-3-639-10059-4
The ability to control nonspecific protein adsorption
at interfaces is a key issue in the design of
biosensors, assays, chromatographic separations and
implant materials. The research presented in this
manuscript focuses on the effect of surface
composition on the properties of adsorbed protein
layers and the probing of protein-protein
interactions both on adsorbed surfaces and in
solution. Monolayers of alkanethiols on gold formed
from solution self-assembly and microfluidic
patterning using poly(dimethyl) siloxane (PDMS)
served as platform for protein adsorption. We are
employed surface plasma resonance (SPR) imaging and
infrared reflection absorption spectroscopy (IRRAS)
to probe the conformation and orientation of adsorbed
proteins, as well as, the characterization of protein
layers.
at interfaces is a key issue in the design of
biosensors, assays, chromatographic separations and
implant materials. The research presented in this
manuscript focuses on the effect of surface
composition on the properties of adsorbed protein
layers and the probing of protein-protein
interactions both on adsorbed surfaces and in
solution. Monolayers of alkanethiols on gold formed
from solution self-assembly and microfluidic
patterning using poly(dimethyl) siloxane (PDMS)
served as platform for protein adsorption. We are
employed surface plasma resonance (SPR) imaging and
infrared reflection absorption spectroscopy (IRRAS)
to probe the conformation and orientation of adsorbed
proteins, as well as, the characterization of protein
layers.
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