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There are certain strains of bacteria mould and yeast have a health benefits for humans (called functional cultures), The health benefits of functional cultures are expressed their actions either directly through the interactions of ingested live microorganisms with the host (probiotic effect) or indirectly as the result of the ingestion of microbial metabolites synthesized during fermentation (biogenic effect). The role of probiotics has expanded from use in gut health maintenance and supplementation in the event of dysbiosis (microfloral imbalance) during antibiotic therapy, to a wide range of health applications.