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The culture of organisms in water (fresh, brackish, or marine) by humans is known as aquaculture. Economic, technological, biological, and environmental factors all influence aquaculture productivity. There has been much discussion on the idea of biological disease control, especially when it comes to the use of microbiological modulators to prevent illness. Probiotics are defined as "organisms and substances that contribute to intestinal microbial balance" in his original definition. Probiotics were created and applied to aquaculture for both environmental and consumer health reasons. A probiotic is a bacterial supplement made up of one or more cultures of specific, non-pathogenic strains of bacteria. A wide variety of live microorganisms, including yeasts, photosynthetic bacteria, lactic acid bacteria, and various Gram-positive and Gram-negative bacteria, are included in probiotics. When added to ponds or tanks in sufficient quantities, they may improve the health of the organisms being cultivated in aquaculture.