Gayatri Behera, Jayashree Behera, Binapani Barik

Process Development of Amlodipine and Olmesartan Medoxomil Tablets

Process Development of Amlodipine and Olmesartan Medoxomil Tablets 10/40 Mg

• Broschiertes Buch

Produktbeschreibung

The present study was focused on process development of amlodipine and olmesartan medoxomil tablet 10/40mg. Amlodipine and Olmesartan medoxomil is a combination of a calcium channel blocker and an angiotensin II receptor antagonist used to treat high blood pressure . The Content uniformity was found of both the drugs were performed. Release study was conducted in pH 6.8 buffer media. Furthermore, dissolution profile comparison was carried out using similarity factor (f2) and the similarity factor of Amlodipine and Olmesartan Medoxomil found to be 73. Other studies Like DSC and FTIR studies reported compatibility of Amlodipine besylate with excipients like Cross Carmel lose sodium was performed shows no chemical interaction between drug and excipients. Dissolution profile of Test and Reference standard found to be similar, Similarity factor (f2) is 73.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 72
• Erscheinungstermin: 8. Februar 2021
• Englisch
• Abmessung: 220mm x 150mm x 5mm
• Gewicht: 113g
• ISBN-13: 9786203409338
• ISBN-10: 6203409332
• Artikelnr.: 61289592

Autorenporträt

La Sra. Gayatri Behera M. Pharm está trabajando como profesora asistente en la Escuela de Farmacia, Universidad de Tecnología de Centurión, Odisha. Participa activamente en la metodología de la investigación. MS. Binapani Barik M. Pharm está trabajando como profesor asistente en la Escuela de Farmacia, Universidad de Tecnología de Centurion, Odisha.