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The book is devoted to developing IgY-Technology which uses the egg yolk of laying hens. This technology is based on the principles of 3 R. Also, chickens are not subjected to euthanasia, and egg yolk is a reservoir of polyclonal antibodies. The author focused on products immunospecificity antibodies, i.e. schemes of immunization as a basic stage of obtaining IgY. Although the extraction and further purification of the immunoglobulin sufficiently described, is currently in search of improvement methods for the isolation of IgY. In addition, the use of cheap chicken antibodies against various infections and as an antidot to natural poisons.