The work is undertaken, to isolate and screen potent bio active metabolites producing Actinomycetes from mangrove habitats by employing the selective screening methods, the potential isolates will be identified by various morphological, biochemical and microscopic methods and also to detect antimicrobial activities as well as isolation, purification and structural elucidation of bioactive metabolites produced by Streptomyces cheonanensis VUK-A.