Heart failure is a serious disease with high mortality. The objective of this study was to identify prognostic factors in heart failure. Method: this was a case-control study carried out over a period of 24 months (from January 2017 to December 2018). Cases are patients hospitalized for heart failure with reduced ejection fraction and died during hospitalization and controls are patients hospitalized for heart failure with reduced ejection fraction and who were discharged alive.Personal history of heart failure was more represented in cases (72%) than in controls (59%) (p < 0.001 and OR = 3.78). The average length of hospital stay for our study population was 10.2 ± 0.5 days. Almost all cases (92.59%) were admitted with NYHA stage III and IV dyspnea (p= 0.004, OR= 2.8). The overall mean systolic blood pressure was 106.6 ± 2.1 mmHg (80 mmHg ± 4.4 in cases and 115.4 mmHg ± 1.8 in controls, p = 0.000 OR = 4.6).