This volume provides comprehensive information on how mapping an individual's epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can be applied in drug development and…mehr
This volume provides comprehensive information on how mapping an individual's epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can be applied in drug development and for better diagnosis and prognosis of diseases. Prognostic Epigenetics is the most-inclusive volume to-date specifically dedicated to epigenetic markers that have been developed for prognosis of diseases, recent advances in this field, the clinical implementation of this research, and the future outlook.
1. It is more than simple genes: The epigenome is more powerful than your genome 2. Diagnostic, prognostic and therapeutic potential of the inter-individual variability in the major epigenetic processes: A Clinical Prospective 3. Technological advances in studying epigenetics biomarkers for clinical research 4. DNA methylation and Chromatin remodeling: Potential prognostic biomarker for disease diagnosis 5. Use of post-translational histone modifications for disease diagnosis 6. Use of non-coding RNAs as Clinical Biomarkers for disease diagnosis 7. The Epigenetic Landscape in Neurological and Neurodegenerative Disorders 8. Epigenetic Biomarkers in Asthma and Allergy 9. Epigenetics Biomarkers in Metabolic syndrome and Obesity 10. Chromatin landscape and Epigenetic biomarkers for clinical diagnosis and prognosis of Type 2 Diabetes mellitus 11. Epigenetic biomarkers in Cardiovascular disorders 12. Epigenetic biomarkers in Cancer 13. Epigenetics in Infectious diseases 14. Epigenetics of autoimmune disorders 15. Epigenetics of Birth defects 16. Epigenetics of adverse pregnancy outcomes 17. Epigenetic landscape of Infertility 18. Epigenetic landscape of polycystic ovarian syndrome 19. Epigenetic biomarkers in ocular disorders 20. Epigenetic biomarkers in personalized medicine 21. Conclusions and Perspectives. Future Challenges and Prospects for Prognostic Epigenetics and personalized epigenomics
1. It is more than simple genes: The epigenome is more powerful than your genome 2. Diagnostic, prognostic and therapeutic potential of the inter-individual variability in the major epigenetic processes: A Clinical Prospective 3. Technological advances in studying epigenetics biomarkers for clinical research 4. DNA methylation and Chromatin remodeling: Potential prognostic biomarker for disease diagnosis 5. Use of post-translational histone modifications for disease diagnosis 6. Use of non-coding RNAs as Clinical Biomarkers for disease diagnosis 7. The Epigenetic Landscape in Neurological and Neurodegenerative Disorders 8. Epigenetic Biomarkers in Asthma and Allergy 9. Epigenetics Biomarkers in Metabolic syndrome and Obesity 10. Chromatin landscape and Epigenetic biomarkers for clinical diagnosis and prognosis of Type 2 Diabetes mellitus 11. Epigenetic biomarkers in Cardiovascular disorders 12. Epigenetic biomarkers in Cancer 13. Epigenetics in Infectious diseases 14. Epigenetics of autoimmune disorders 15. Epigenetics of Birth defects 16. Epigenetics of adverse pregnancy outcomes 17. Epigenetic landscape of Infertility 18. Epigenetic landscape of polycystic ovarian syndrome 19. Epigenetic biomarkers in ocular disorders 20. Epigenetic biomarkers in personalized medicine 21. Conclusions and Perspectives. Future Challenges and Prospects for Prognostic Epigenetics and personalized epigenomics
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