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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. In contrast to necrosis, which is a form of cell-death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process which generally confers advantage during an organism''s life-cycle. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.