This book delivers an update molecular mechanism of vascular calcification and bone mineralization, and the comparative discussion on several anti-calcifying agents for treatment of vascular/arterial calcification. This modern book has been framed for students, researchers, and also for the patients, and also offers an excellent source of references. This book highly focuses on the impact of natural extracts for the treatment of vascular calcification. Omega-3 fatty acids have very fewer complications as compared to anti-calcifying agents such as bisphosphonates. This book has addressed the future perspectives of omega-3 fatty acids for the control of vascular calcification and bone deterioration. Omega-3 fatty acids might target a key pathway which seems to enhance vascular calcification as well as bone decay. Therefore blocking this signaling may serve as a novel interventional strategy to prevent vascular calcification without debilitating bone quality.