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High Quality Content by WIKIPEDIA articles! Protein structure prediction is the prediction of the three-dimensional structure of a protein from its amino acid sequence that is, the prediction of a protein's tertiary structure from its primary structure (structure prediction is fundamentally different from the inverse, and less difficult, problem of protein design). Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry. Protein structure prediction is of high importance in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes). Every two years, the performance of current methods is assessed in the CASP experiment.