With three Nobel Laureates contributing to this invaluable collection of high-quality articles, carefully selected from the highly praised R.A. Meyer's Encyclopedia, these two volumes cover a wide range of topics in protein research. Clearly divided into sections on structure, modeling, expression, analysis and others, the chapters are designed to aid readers of all levels of expertise: Each chapter includes a glossary of the most important keywords, a concise summary of the article concerned and comprehensive references for further reading. Similarly, the uniform structure of the articles…mehr
With three Nobel Laureates contributing to this invaluable collection of high-quality articles, carefully selected from the highly praised R.A. Meyer's Encyclopedia, these two volumes cover a wide range of topics in protein research. Clearly divided into sections on structure, modeling, expression, analysis and others, the chapters are designed to aid readers of all levels of expertise: Each chapter includes a glossary of the most important keywords, a concise summary of the article concerned and comprehensive references for further reading. Similarly, the uniform structure of the articles makes them very easy to use, resulting in a ready reference for molecular and cell biologists, biochemists, biophysicists, and biotechnologists, as well as those working in the pharmaceutical and biotechnological industries.
Robert A. Meyers obtained his Ph.D. in Chemistry at the University of California at Los Angeles. He was a post-doctoral fellow at the California Institute of Technology and has more than 17 patents, 50 technical papers and 12 books to his name. As Editor-in-Chief he conceived and edited several ambitious multivolume reference works.
Inhaltsangabe
VOLUME 1 I STRUCTURE AND FUNCTION Macromolecules, X-Ray Diffraction of Biological Protein NMR Spectroscopy Electron Microscopy of Biomolecules Circular Dichroism in Protein Analysis Protein Structure Analysis: High-throughput Approaches Aggregation, Protein Prions Alzheimer's Disease Chaperones, Molecular Motor Proteins DNA-Protein Interactions II MODELLING AND DESIGN Protein Modeling Synthesis of Peptide Mimetics and their Building Blocks Design and Application of Synthetic Peptides Synthetic Peptides: Chemistry, Biology, and Drug Design III EXPRESSION, SYNTHESIS AND DEGRADATION Ribosome, High Resolution Structure and Function Ubiquitin-Proteasome System for Controlling Cellular Protein Levels Plant-based Expression of Biopharmaceuticals Cell-free Translation Systems VOLUME 2 I ANALYTICAL TECHNIQUES HPLC of Peptides and Proteins Protein Purification Gel Electrophoresis, 2D-Difference Proteomics Mass Spectrometry-based Methods of Proteome Analysis Protein Microarrays Informatics (Computational Biology) Nucleic Acid and Protein Single Molecule Detection and Characterization Footprinting Methods to Examine the Structure and Dynamics of Proteins II SIGNALLING AND REGULATION Biological Regulation by Protein Phosphorylation Intracellular Signaling in Cancer Receptor Biochemistry Signal Transduction Mediated by Heptahelical Receptors and Heterotrimeric G Proteins Growth Factors Cytokines: Interleukins Viral Inhibitors and Immune Response Mediators: The Interferons Molecular Mediators: Cytokines
VOLUME 1 I STRUCTURE AND FUNCTION Macromolecules, X-Ray Diffraction of Biological Protein NMR Spectroscopy Electron Microscopy of Biomolecules Circular Dichroism in Protein Analysis Protein Structure Analysis: High-throughput Approaches Aggregation, Protein Prions Alzheimer's Disease Chaperones, Molecular Motor Proteins DNA-Protein Interactions II MODELLING AND DESIGN Protein Modeling Synthesis of Peptide Mimetics and their Building Blocks Design and Application of Synthetic Peptides Synthetic Peptides: Chemistry, Biology, and Drug Design III EXPRESSION, SYNTHESIS AND DEGRADATION Ribosome, High Resolution Structure and Function Ubiquitin-Proteasome System for Controlling Cellular Protein Levels Plant-based Expression of Biopharmaceuticals Cell-free Translation Systems VOLUME 2 I ANALYTICAL TECHNIQUES HPLC of Peptides and Proteins Protein Purification Gel Electrophoresis, 2D-Difference Proteomics Mass Spectrometry-based Methods of Proteome Analysis Protein Microarrays Informatics (Computational Biology) Nucleic Acid and Protein Single Molecule Detection and Characterization Footprinting Methods to Examine the Structure and Dynamics of Proteins II SIGNALLING AND REGULATION Biological Regulation by Protein Phosphorylation Intracellular Signaling in Cancer Receptor Biochemistry Signal Transduction Mediated by Heptahelical Receptors and Heterotrimeric G Proteins Growth Factors Cytokines: Interleukins Viral Inhibitors and Immune Response Mediators: The Interferons Molecular Mediators: Cytokines
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