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Pseudorabies virus (PRV) is an important swine pathogen that impacts the swine industry worldwide. PRV belongs to the alphaherpes virus subfamily of the herpesviruses and has been widely used as a model for herpes virus. Most recently, PRV has been reported to sporadically spillover into humans and other animals. This book collates the lastest advances in the field of pseudorabies virus research, including critical reviews and research on viral epidemiology, virus-host interaction, pathogenesis and immunity, and novel antiviral strategies.