Regenerative endodontics presents a new era in biological and clinical endodontics. Currently, this biologically based treatment is being recognized as the first treatment choice for immature teeth with pulp necrosis. Induced generation and regeneration of vital tissues in the pulp space can thicken the root structure leading to a stronger tooth with a potentially reduced fracture risk. Apexification procedure may no longer be the preferred first option to treat immature permanent teeth with non vital pulps. Revascularization represents a recent and promising treatment modality that has been in evidence due to the preservation of biological principles and the possibility of minimizing the treatment period of immature teeth.