QSAR study of chemotherapeutic agents - Sharma, Meenakshi;Agarwal, Anshu;Soni, Vatsala
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The objective of drug discovery phase is to synthesize lead compounds, new analogs with improved potency, reduced off target activities and physio-chemical/metabolic properties suggestive of reasonable in-vivo pharmacokinetics. The goal of present work is to design drug with minimum side effect and maximum potency. 2D QSAR is planned using Multiple Linear Regression Analysis, for achieving the goal, which can help in recognizing the important descriptor that can help in increasing the potency of anticancer drug.

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Produktbeschreibung
The objective of drug discovery phase is to synthesize lead compounds, new analogs with improved potency, reduced off target activities and physio-chemical/metabolic properties suggestive of reasonable in-vivo pharmacokinetics. The goal of present work is to design drug with minimum side effect and maximum potency. 2D QSAR is planned using Multiple Linear Regression Analysis, for achieving the goal, which can help in recognizing the important descriptor that can help in increasing the potency of anticancer drug.
Autorenporträt
Meenakshi Sharma, M.Sc. Pharmaceutical Chemistry from Banasthali University and currently submitted Ph.D thesis in Chemistry in Banasthali University, Rajasthan.Her area of interest are synthetic medicinal chemistry and drug design.