Sanam Shah, a mathematician, and Ariel Spiegel, a biologist, are Ph.D. candidates and best friends working together to discover the cause of colony collapse disorder - the urgent, ecological crisis where bees are disappearing around the world in alarming numbers. Just as they are about to publish a career-defining new paper on the subject, calling for a ban on commercial pesticides, Sanam realizes that the numbers don't add up to support their conclusion. Should she look the other way for the sake of environmental action, or should she stand by her scientific principles, even if it means ceding ground to an ecological disaster, jeopardizing her career and losing her best friend?