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This Book is mainly used for the interest of postgraduate, research scholar in Chemistry, Biochemistry and Molecular Biology students. The effort has been made to explore multidisciplinary work in the field of synthetic organic chemistry and molecular biology for the development of novel anticancer drugs with potential medicinal or biological applications. Therefore, some of heterocyclic Quinoline derivatives such as substituted Hydrazones, Thiadiazoles, Thiazolidinones and its DNA Binding Interaction Studies which is very important for their abilities to act as potential drugs.