Vakhid A. Mamedov

Quinoxalines

Synthesis, Reactions, Mechanisms and Structure

• Broschiertes Buch

Produktbeschreibung

Thisbook reviews the fundamental aspects of quinoxaline chemistry: synthesis,reactions, mechanisms, structure, properties, and uses. The first four chapterspresent a survey of the developments in quinoxaline chemistry since thepublication of the monograph on "Condensed Pyrazines" by Cheeseman and Cooksonin 1979. These chapters give comprehensive coverage of all the methods of the synthesis of quinoxalinesand the important quinoxaline-containing ring systems suchas thiazolo[3,4-a]-, pyrrolo[1,2-a]-, and imidazo[1,5-a]quinoxalines.Chapter five describes many new methods for the construction of quinoxalinemacrocycles, which are important in applications such as optical devices andmaterials. The final chapter reviews all previously known rearrangements ofheterocyclic systems that lead to benzimidazole derivatives. Mamedov criticallyanalyses these transformations to reveal a novel acid-catalyzed rearrangementof quinoxalinones giving 2-heteroarylbenzimidazoles and1-heteroarylbenzimidazolones in the presence of nucleophilic reactants (MAMEDOVHeterocycle Rearrangement). This book is of interest to researchers in thefields of heterocyclic and synthetic organic chemistry.

Produktdetails

• Verlag: Springer / Springer International Publishing / Springer, Berlin
• Artikelnr. des Verlages: 978-3-319-80651-8
• Softcover reprint of the original 1st ed. 2016
• Seitenzahl: 456
• Erscheinungstermin: 27. Mai 2018
• Englisch
• Abmessung: 235mm x 155mm x 25mm
• Gewicht: 694g
• ISBN-13: 9783319806518
• ISBN-10: 3319806513
• Artikelnr.: 53571875

Autorenporträt

Vakhid A. Mamedov is the Head of Laboratory for the Chemistry of Heterocycles at the Kazan Scientific Centre of the Russian Academy of Sciences. His research is dedicated to quinoaxilines. After his graduation from the Azerbaijan State University in Baku (1981) and working at the Institutes of Physics and of Petroleum and Chemical Processes (1981-1982) of the Azerbaijan Academy of Sciences, he moved to Kazan in 1985, where he received his Ph.D (1989), and D.Sc. (1999) degrees in chemistry, working with the Professors Il¿dus A. Nuretdinov, Eugeniy A. Berdnikov and Yakov A. Levin. He spent a postdoctoral fellowship (1997-1998) with Professor Sadao Tsuboi at the Okayama University (Japan), working on synthetic approaches to the C-13 side chain of paclitaxel (Taxol) and docetaxel (Taxotere). He became head of laboratory of the Chemistry of Heterocyclic Compounds in IOPC in 2002. He was principal tutor of 10 post-graduated and 24 graduated students, both in Russia and Japan. He authored over 170 papers. Mamedov¿s research interests focus on the methodology of organic synthesis, development of new schemes of the tandem transformations for synthesizing the diversity-oriented heterocyclic systems. 

Inhaltsangabe

Introduction: Quinoxaline as a Parent Heterocycle.- Synthesis of Quinoxalines.- Synthesis ofPyrrolo[l,2-a]quinoxalines.- Synthesisof Imidazo[1,5-a]- and Imidazo[1,2-a]quinoxalines.- Synthesis ofQuinoxaline Macrocycles.- Rearrangements of Quinoxalin(on)es in the Synthesisof Benzimidazol(on)es.- Appendix.

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Introduction: Quinoxaline as a Parent Heterocycle.- Synthesis of Quinoxalines.- Synthesis of Pyrrolo[l,2-a]quinoxalines.- Synthesis of Imidazo[1,5-a]- and Imidazo[1,2-a]quinoxalines.- Synthesis of Quinoxaline Macrocycles.- Rearrangements of Quinoxalin(on)es in the Synthesis of Benzimidazol(on)es.- Appendix.