Glioblastoma multiforme (GBM) is the most aggressive
form of primary brain tumor. Numerous studies have
tried to
explore various avenues to make this tumor sensitive
to radiation
therapy and improve the prognosis for patients with
this tumor.
However, the prognosis for patients with this tumor
remains poor
with median survival time less than one year.
By using current concepts and techniques of local
drug delivery to the brain to sensitize the tumor to
radiation
therapy, we were able to greatly improve the median
survival time in
an animal model.
form of primary brain tumor. Numerous studies have
tried to
explore various avenues to make this tumor sensitive
to radiation
therapy and improve the prognosis for patients with
this tumor.
However, the prognosis for patients with this tumor
remains poor
with median survival time less than one year.
By using current concepts and techniques of local
drug delivery to the brain to sensitize the tumor to
radiation
therapy, we were able to greatly improve the median
survival time in
an animal model.