This book documents the most important clinicopathological features of rare thyroid tumours with an emphasis (and ample documentation) on their histological and immunohistochemical aspects. Whenever necessary, namely for differential diagnosis and/or therapy purposes, molecular data are also highlighted. In order to understand the histogenesis of rare lesions and to be able to make a differential diagnosis, the editors use the WHO book for endocrine tumours (in preparation) as a framework for classifying thyroid tumours. In addition to characterizing the main histotypes of thyroid tumours,…mehr
This book documents the most important clinicopathological features of rare thyroid tumours with an emphasis (and ample documentation) on their histological and immunohistochemical aspects. Whenever necessary, namely for differential diagnosis and/or therapy purposes, molecular data are also highlighted. In order to understand the histogenesis of rare lesions and to be able to make a differential diagnosis, the editors use the WHO book for endocrine tumours (in preparation) as a framework for classifying thyroid tumours. In addition to characterizing the main histotypes of thyroid tumours, this book also provides detailed information on how to approach the diagnosis of tumours according to the major morphological/immunohistochemical characteristics, the predominant morphology and whether or not they are hereditary. This book is a valuable learning tool for those involved in the differential diagnosis of thyroid lesions.
Manuel Sobrinho-Simões MD, PhD, is co-founder and Director of IPATIMUP, Porto, Portugal. He is also Professor and Director of the Department of Pathology and Oncology of the Medical Faculty of the University of Porto, Portugal. His research interests are focused on thyroid cancer pathology: aetiopathogenesis,diagnosis, prognosis and therapy selection. He was President of the European Society of Pathology from 1999-2001 and is co-author of the 2nd, 3rd and 4th edition of the WHO book on endocrine tumours (1988, 2004 and 2016 (in preparation)). Manuel Sobrinho-Simões was voted the most influential pathologist in the World (2015) in a poll conducted by "The Pathologist". José Manuel Cameselle-Teijeiro, MD, PhD, is a member of the Department of Anatomic Pathology at the Clinical University Hospital in Santiago de Compostela, Spain, and is Associate Professor of the Medical School there. His research interests are focused on thyroid tumors pathology, with an emphasis on familial non-medullary thyroid cancer. He coordinates the Spanish Society of Anatomic Pathology`s Working Group on Endocrine Pathology and has co-authored several chapters of the 3rd and 4th editions of the WHO book on endocrine tumours. Catarina Eloy, MD, PhD, is Professor of Pathology at the University of Porto, Portugal, and serves as Medical Director of the IPATIMUP Diagnostic Unit. Her doctoral thesis was on papillay thyroid carcinoma and she is a co-author of the next WHO book on endocrine tumors (in preparation). Her research interests are focused on thyroid cancer pathology: etiopathogenesis, cytopathology and molecular pathology.
Inhaltsangabe
Introduction.- Clinical Features.- Patient Examination.- Sampling Methods.- Rare variants of Papillary Carcinoma (PTCs).- Rare variants of Follicular Carcinoma (FTCs).- Rare variants of Hürthle cell (oncocytic) carcinoma.- Rare variants of Medullary carcinoma (MTCs).- Rare variants of poorly differentiated carcinoma.- Epithelial and border-line epithelial tumors.- Soft Tissue Tumors.- Lympho-hematopoietic Tumors.- Other Tumors.- Rare Benign Tumors and rare tumor-like conditions.- Therapeutic options.- Conclusions.- Diagram for differential diagnosis based on the predominant morphology.
