ras Oncogenes

Herausgegeben:Spandidos, D.

• Broschiertes Buch

Produktbeschreibung

Structure and Organization of the ras Gene Family, in Human.- Transcriptional Regulatory Sequences in the H-ras1 Gene.- Mutational Activation of Human ras Genes.- Early Detection of ras Oncogenes Activated by Chemical Carcinogentreatment.- Ras Mutations in Primary Myelodysplasia and in Patients Following Cytotoxic Therapy.- High Frequency of ras Oncogene Activation in Benign and Malignant Human Thyroid Tumours.- Alterations of C-Ha-ras Gene are Associated with c-myc Activation in Human Cervical Cancers.- Human Thyroid Neoplasms Express ras p21 Protein at High Levels.- Detection of Mutations in the H-ras Proto-Oncogene in Liver Tumours of the CF1 Mouse.- Analysis of Hras1-Associated Polymorphisms and Segregation of Taq1-Defined Alleles in Different Human Tumors.- DNA Methylation of the Human Hras1 Gene.- Structure of the Drosophila ras2 Bidirectional Promoter.- The rap Proteins : GTP Binding Proteins Related to p21 ras with a Possible Reversion Effect on ras Transformed Cells.- Suppression of Temperature-Sensitive RAS in S.cerevisiae by a Putative Protein Kinase.- The Function of the Mammalian ras Proteins.- Ras Proteins as Potential Activators of Protein Kinase C Function.- Novel Phosphorylation of ras p21 and Mutational Studies.- The Role of p21ras in Proliferative Signal Transduction.- Characterization of ras Proteins Produced at High Levels in the Baculovirus Expression System.- Phenotypic and Cytogenetic Alterations in Human Skin Keratinocytes after Transfection with the Cellular Harvey-ras (c-Ha-ras) Oncogene.- Regulation of Cell Death by ras and myc Oncogenes.- Ras-Induced Phenotypic Changes in Human Fibroblasts.- Suppression of ras Oncogene Expression Using Sequence Specific Oligodeoxynucleotides.- Expression of ras, myc and fos Oncogenes During the DMSO-Induced Detransformation of a Colon Carcinoma Line (HT29).- The ras Oncogene and Myogenic Commitment and Differentiation.- Tumorigenic Conversion of in vivo Differentiation Competent Mammary Cells by Introduction and Expression of ras or mil(raf) but not myc.- Activation of the Human c-Ha-ras-1 Gene by Chemical Carcinogens in vitro.- Activation of ras Oncogenes During Colonic Carcinogenesis: Detection by the Polymerase Chain Reaction.- Post-Translational Modification of ras Proteins: Palmitoylation and Phosphorylation of Yeast ras Proteins.- Molecular Interactions of p21.- Ras-Transformed Cells Contain Microtubules Rich in Modified ?-Tubulin in Their Trailing Edges.- Glutathione S-Transferase/ras Fusion Protein: A Tool for Affinity Chromatography of ras Associated Proteins.- Aristolochic Acid I Induced Tumors in Wistar Rats Contain Activating Mutations in Codon 61 of the H-ras Protooncogene.- ?-Adrenoceptor is Required for Activation of Avian Erythrocyte GS by Guanine Nucleotides.- Expression of ras Oncogene in Xenopus laevis.- An Appraisal of Four Monoclonal Antibodies Used in the Immunohistochemical Detection of ras p21.- Identification of a Protein Interacting with ras-p21- by Chemical Cross-Linking.- Isolation and Partial Characterization of a New Gene (br1) Belonging to the Superfamily of the Small GTP-Binding Proteins.- Structural Investigations on the G-Binding Domain of p21.- Molecular Biology of GAP and its Interaction with Oncogenic ras p21.- The Cooperation between Viral ras Genes and Different Immortalizing Genes Induces the Transformation of Rat Thyroid Epithelial Cells.

Produktdetails

• Verlag: Springer / Springer US / Springer, Berlin
• Artikelnr. des Verlages: 978-1-4757-1237-7
• Softcover reprint of the original 1st ed. 1989
• Seitenzahl: 336
• Erscheinungstermin: 15. April 2013
• Englisch
• Abmessung: 254mm x 178mm x 19mm
• Gewicht: 634g
• ISBN-13: 9781475712377
• ISBN-10: 1475712375
• Artikelnr.: 39566363

Inhaltsangabe

Structure and Organization of the ras Gene Family, in Human.- Transcriptional Regulatory Sequences in the H-ras1 Gene.- Mutational Activation of Human ras Genes.- Early Detection of ras Oncogenes Activated by Chemical Carcinogentreatment.- Ras Mutations in Primary Myelodysplasia and in Patients Following Cytotoxic Therapy.- High Frequency of ras Oncogene Activation in Benign and Malignant Human Thyroid Tumours.- Alterations of C-Ha-ras Gene are Associated with c-myc Activation in Human Cervical Cancers.- Human Thyroid Neoplasms Express ras p21 Protein at High Levels.- Detection of Mutations in the H-ras Proto-Oncogene in Liver Tumours of the CF1 Mouse.- Analysis of Hras1-Associated Polymorphisms and Segregation of Taq1-Defined Alleles in Different Human Tumors.- DNA Methylation of the Human Hras1 Gene.- Structure of the Drosophila ras2 Bidirectional Promoter.- The rap Proteins : GTP Binding Proteins Related to p21 ras with a Possible Reversion Effect on ras Transformed Cells.- Suppression of Temperature-Sensitive RAS in S.cerevisiae by a Putative Protein Kinase.- The Function of the Mammalian ras Proteins.- Ras Proteins as Potential Activators of Protein Kinase C Function.- Novel Phosphorylation of ras p21 and Mutational Studies.- The Role of p21ras in Proliferative Signal Transduction.- Characterization of ras Proteins Produced at High Levels in the Baculovirus Expression System.- Phenotypic and Cytogenetic Alterations in Human Skin Keratinocytes after Transfection with the Cellular Harvey-ras (c-Ha-ras) Oncogene.- Regulation of Cell Death by ras and myc Oncogenes.- Ras-Induced Phenotypic Changes in Human Fibroblasts.- Suppression of ras Oncogene Expression Using Sequence Specific Oligodeoxynucleotides.- Expression of ras, myc and fos Oncogenes During the DMSO-InducedDetransformation of a Colon Carcinoma Line (HT29).- The ras Oncogene and Myogenic Commitment and Differentiation.- Tumorigenic Conversion of in vivo Differentiation Competent Mammary Cells by Introduction and Expression of ras or mil(raf) but not myc.- Activation of the Human c-Ha-ras-1 Gene by Chemical Carcinogens in vitro.- Activation of ras Oncogenes During Colonic Carcinogenesis: Detection by the Polymerase Chain Reaction.- Post-Translational Modification of ras Proteins: Palmitoylation and Phosphorylation of Yeast ras Proteins.- Molecular Interactions of p21.- Ras-Transformed Cells Contain Microtubules Rich in Modified ?-Tubulin in Their Trailing Edges.- Glutathione S-Transferase/ras Fusion Protein: A Tool for Affinity Chromatography of ras Associated Proteins.- Aristolochic Acid I Induced Tumors in Wistar Rats Contain Activating Mutations in Codon 61 of the H-ras Protooncogene.- ?-Adrenoceptor is Required for Activation of Avian Erythrocyte GS by Guanine Nucleotides.- Expression of ras Oncogene in Xenopus laevis.- An Appraisal of Four Monoclonal Antibodies Used in the Immunohistochemical Detection of ras p21.- Identification of a Protein Interacting with ras-p21- by Chemical Cross-Linking.- Isolation and Partial Characterization of a New Gene (br1) Belonging to the Superfamily of the Small GTP-Binding Proteins.- Structural Investigations on the G-Binding Domain of p21.- Molecular Biology of GAP and its Interaction with Oncogenic ras p21.- The Cooperation between Viral ras Genes and Different Immortalizing Genes Induces the Transformation of Rat Thyroid Epithelial Cells.