The naturally occurring twenty amino acids are used by nature to generate diverse set of biomolecules. They are able to perform the specific functions of life because they can adopt particular folded structure. In order to understand the principle of folding scientists have started to look for designing of various novel synthetic oligomers which can mimic the structure and function of biomolecules (Foldamers). With the increasing time spent in understanding the principles of folding many synthetic oligomers are reported with dazzling architectures and recently foldamres which can perform many specific functions such as catalysis are also reported.