The main problem in the Nile River basin today is the threat to the water security of the basin States as there is no permanent mechanism (legal and institutional) arrangement acceptable to the basin States to enable cooperation in the management and equitable use of the Nile waters. This book has analysed the current Nile basin problem and provided the way forward for the development of acceptable new Nile River Basin Regime based on the prevailing international water law, and use of science to inform the policy in order to provide guiding principles, norms and rules to ensure cooperation, joint planning, equitable use of the shared Nile basin water resources and causing no significant harm for peaceful coexistence of the basin States. The known annual Nile River flow of 84 billion cubic metres is today considered to have been developed all by two basin States of Egypt and the Sudan while the upper basin States especially Ethiopia is at its peak of developing the same shared Nile water resources. This book therefore, has development a new Nile River Basin Regime that will enable the Basin States to balance the existing water uses and potential water uses.