This monograph focuses on the design of low complexity interference cancellation and channel estimation algorithms for two different space-frequency coded OFDM system configurations. The first of these configurations is space-frequency block coded OFDM (SFBC-OFDM) which yields performance improvement mainly by exploiting spatial diversity. To attain further performance improvement, a concatenated SFBC-OFDM system configuration, which exploits both spatial and frequency diversities inherent in multiple-input multiple-output multi-path channels, is considered next. In addition to presenting computationally efficient receiver designs for the two above-mentioned system configurations, the monograph also investigates the performance of the proposed receivers via accurate analytical and simulation methods under various channel conditions. Furthermore, the performances and complexities associated with the designed receiver structures are quantified and compared with those corresponding to the receivers that already exist in the literature.